Huge Study: Statins Associated with Cataracts, Not Dementia

Statin drugs are a family of medications known to reduce the risk of heart attack and death in people with cardiovascular disease. The drugs usually can be identified by the letters “statin” in their names. They include simvastatin, atorvastatin, fluvastatin, pravastatin, and rosuvastin.

Many have worried that statins might increase the risk of dementia, or cancer, or some other serious medical condition, and there have been studies that support those concerns. However, those studies are relatively small. A very large study would be necessary to truly understand the possible risks of taking statin drugs.

The British health care system provides the opportunity to gather huge amounts of data. Medical practices in England and Wales typically use electronic health records.

To look precisely at the issue of the risks of using statins, investigators collected data on almost two million people from over 300 general practices. About 225,000 people, about 10% of the subjects, were new users of one of the statin drugs. Data over five years were used.
The researchers presented their data mostly as relative risks. The five year risk of cataract in a person not using a statin was 0.0495. This means that for 100 people, about five would usually get cataract. Among people using a statin, the five year risk was about a third more, or between six and seven cases in 100 people. Put another way, treating 1000 people with a statin would produce about 19 “extra” cataract cases.

Meantime, the benefit would be a reduced risk of heart attack and sudden death. For every 100 users, about three people would be spared from a new cardiovascular event. Put another way, treating 1000 people with a statin would prevent 27 new cardiovascular cases.

Statin Use Did Not Affect Cancer Risk

There was no association with taking statin medications and the following cancers:

Colon cancer
Kidney cancer
Stomach cancer
Lung cancer
Melanoma
Breast cancer
Prostate cancer

Statin users had a slightly reduced risk of cancer of the esophagus.

Statin Use Associated with Liver, Kidney and Muscle Problems

A few medical conditions were associated with statin use, as previously known and expected. These were:

Liver dysfunction
Kidney failure
Myopathy (muscle inflammation)

Statin Use Not Associated with Osteoporosis, Parkinson’s, Blood Clots

Other conditions for which no association with statin use was found include: dementia, Parkinson’s disease, osteoporotic fractures, and rheumatoid arthritis. The risks and benefits of taking statin medications must be evaluated in light of personal goals and preferences, and in the context of frank discussion with the health care provider.

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Treating Insect Bites

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Green Superheroes

Romaine. (Cancer Prevention) This celery-flavored green is one of the best vegetable sources of beta-carotene—712 micrograms per cup. Recent studies showed that high levels of beta-carotene impends the growth of prostate cancer cells by 50 percent. Arugula (Bone Health) . One cup of these mustard-flavored leaves has 10 percent of the bone-building mineral that can be in a glass of whole milk and 100 percent less saturated fat. There’s also some magnesium which assure more protection against osteoporosis. Watercress (Protects the Pipes) . It’s a pepper-flavored filter for your body. Watercress contains phytochemicals that may stop cigarette smoke and other airborne pollutants from causing lung cancer. Endive (Heart Health) . It’s slightly bitter but it offers twice the fiber of iceberg lettuce. A cup of endive also provides almost 20 percent of your day by day requirement of folate. People who don’t get enough of this vital B vitamin may have a 50 percent greater risk of...

Health & Nutrition Facts for Bodybuilders

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